Adaptive treatment and robust control

Lancaster University partner information:

Funding: EPSRC, £293k of £547k total, 2015–2018

Investigator: Professor C J Taylor (PI)

Project PI: Professor R Henderson (Newcastle University)

In medical research, an adaptive treatment strategy (or adaptive intervention) is a set of rules for choosing effective treatments for individual patients. The treatment choices made for a particular patient are based on that individual’s characteristics and history, with the goal of optimizing his or her long-term clinical outcome. This project involves a three-way collaboration between researchers in statistics, in control engineering, and in mathematical analysis, at Lancaster University and Newcastle University. The aim is to solve an array of problems in the general area of adaptive intervention through the integration of techniques and approaches that have been developed in distinct ways in the three fields. The problems are focused around the cross-disciplinary themes of irregular sampling and robustness.